Swett C
Am J Psychiatry. 1975 May;132(5):532-4. doi: 10.1176/ajp.132.5.532.
Among 1,152 psychiatric inpatients who received a phenothiazine, a butyrophenone, or a thioxanthene, 116 developed dystonia attributed to one or more of these drugs. The highest frequencies of dystonia occurred among recipients of haloperidol and the long-acting injectable fluphenazines. For all patients at risk, dystonia was more common in men and in younger patients. For chlorpromazine, high doses, male sex, and low age were each positively associated with dystonia.
在1152名接受吩噻嗪类、丁酰苯类或硫杂蒽类药物治疗的精神科住院患者中，有116人出现了由这些药物中的一种或多种导致的肌张力障碍。肌张力障碍发生率最高的是接受氟哌啶醇和长效注射用氟奋乃静治疗的患者。在所有有风险的患者中，肌张力障碍在男性和年轻患者中更为常见。对于氯丙嗪，高剂量、男性以及低年龄均与肌张力障碍呈正相关。
