新泽西州艾滋病患者中的癌症

Cancer in people with AIDS in New Jersey.

作者信息

Roché L M, Weinstein R B, Paul S M, Costa S J

机构信息

Cancer Epidemiology Services, New Jersey Department of Health & Senior Services, USA.

出版信息

N J Med. 2001 Jan;98(1):27-36.

PMID:11198110

Abstract

A total of 2,460 persons with AIDS (PWA) and cancer were identified--2,159 men and 301 women--among 22,382 men and 7,931 women reported with AIDS from 1979-1995 in New Jersey. Of these, 50% were diagnosed with Kaposi's sarcoma (KS), 33% with non-Hodgkin's lymphoma (NHL), and the remainder with other cancers, including lung and bronchus, oral, cervical, Hodgkin's disease, and digestive other than anal. The proportions of PWA who also had cancer, specifically KS and NHL, varied significantly by gender, race, and mode of HIV transmission. These findings are discussed in terms of risk factors in addition to immunosuppression that may account for the higher rates of cancer among PWA than the general population. Cancer prevention and detection measures likely will become more important as PWA survive longer.

摘要

在1979年至1995年新泽西州报告的22382名男性和7931名女性艾滋病患者中，共识别出2460名患有艾滋病的癌症患者，其中男性2159名，女性301名。其中，50%被诊断患有卡波西肉瘤（KS），33%患有非霍奇金淋巴瘤（NHL），其余患有其他癌症，包括肺癌和支气管癌、口腔癌、宫颈癌、霍奇金病以及除肛门外的消化系统癌症。同时患有癌症，特别是KS和NHL的艾滋病患者比例因性别、种族和艾滋病毒传播方式的不同而有显著差异。除免疫抑制外，还根据可能导致艾滋病患者中癌症发病率高于普通人群的危险因素对这些发现进行了讨论。随着艾滋病患者存活时间延长，癌症预防和检测措施可能会变得更加重要。