南非白尾鼠糖尿病的肾小球病变
Glomerular lesions of diabetes mellitus in Mystromys albicaudatus.
作者信息
Riley T, Stuhlman R A, Van Peenen H J, Esterly J A, Townsend J F
出版信息
Arch Pathol. 1975 Mar;99(3):167-9.
PMID:1120026
Abstract
The kidneys of 175 nondiabetic and diabetic Mystromys albicaudatus were evaluated histologically by light microscopy. The degree of capillary basement membrane thickening and the predominant glomerular histologic pattern were recorded. Statistical analyses indicated that glomerulosclerosis is associated with diabetes in this species. In addition, a granular capillary basement membrane lesion occurred more frequently in diabetic than in nondiabetic animals.
摘要
通过光学显微镜对175只非糖尿病和糖尿病白尾匙鼠的肾脏进行组织学评估。记录毛细血管基底膜增厚程度和主要的肾小球组织学模式。统计分析表明，该物种的肾小球硬化与糖尿病有关。此外，颗粒状毛细血管基底膜病变在糖尿病动物中比在非糖尿病动物中更频繁出现。
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