[Cytokine profile and fibrinogen level in blood plasma in diabetic foot under the action of heparin].

The investigation displayed in the article was conducted in order of estimating the content of interleukin-1, tumornecrotic factor and fibrinogen in the patients suffering from the I and II type diabetes mellitus complicated by the lower extremity inflammatory-necrotic process. The type II diabetes was shown to have these substances level as higher as the I one, increasing even more at administrating heparin to the patients. The manifestation of hypercoagulative properties of the latter, as it's postulated, is a result of increasing the synthesis of proinflammatory cytokines.