Stepanov Iu M, Gritsenko I I
Dnepropetrovsk State Medical Academy.
Ukr Biokhim Zh (1999). 2000 May-Jun;72(3):87-90.
There was studied prostaglandins E concentration in bioptats of gastric mucosa in 158 patients with various forms and localization of chronic gastritis using a radioimmunological method. Chronic gastritis without atrophy and with mild atrophy showed to have decreased levels of prostaglandins E in comparison with the control. In the patients with atrophic gastritis with "reconstruction" of epithelium there was revealed an increase of prostaglandins concentration, which was maximal in the patients with atrophic-hyperplastic forms of the disease.
采用放射免疫法研究了158例不同类型和部位的慢性胃炎患者胃黏膜活检组织中前列腺素E的浓度。与对照组相比,无萎缩性和轻度萎缩性慢性胃炎患者的前列腺素E水平降低。在伴有上皮“重建”的萎缩性胃炎患者中,发现前列腺素浓度升高,在萎缩性增生型疾病患者中最高。