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妊娠期乳腺癌——我们在吉隆坡大学医院对6例患者的治疗经验。

Breast cancer in pregnancy--our experience with six patients in the University Hospital, Kuala Lumpur.

作者信息

Yip C H, Taib N A, Abdullah M M, Wahid I

机构信息

Department of Surgery, University Hospital, 50603 Kuala Lumpur.

出版信息

Med J Malaysia. 2000 Sep;55(3):308-10.

Abstract

Presentation of breast cancer during pregnancy is a rare situation and one that requires a multidisciplinary approach involving an obstetrician, surgeon and oncologist. Management should be along the same principles as in non-pregnant patients and delay is not justifiable. Mastectomy and axillary clearance is the best option, followed by chemotherapy, which is safe after the first trimester. Radiation if required should be delayed until after delivery of the baby. We present here our experience with 6 patients who presented with breast cancer during pregnancy. Five patients refused any treatment until after delivery, while one underwent only a mastectomy and axillary clearance. The outcome was poor; all of them died between 14 months and 52 months. The poor outcome probably reflects the late stage at presentation in four of the patients (State 3 and 4) rather than the delay in treatment, while delay in treatment in the two who presented with early cancer (Stage 1 and 2) led to a more advanced stage after delivery.

摘要

妊娠期乳腺癌的情况较为罕见,需要产科医生、外科医生和肿瘤学家采取多学科方法进行处理。管理原则应与非妊娠患者相同,不应无故拖延。乳房切除术和腋窝清扫术是最佳选择,随后进行化疗,孕早期过后化疗是安全的。如有必要,放疗应推迟至婴儿出生后。我们在此介绍我们对6例妊娠期乳腺癌患者的治疗经验。5例患者在分娩前拒绝任何治疗,而1例仅接受了乳房切除术和腋窝清扫术。结果很差;她们全部在14个月至52个月之间死亡。不良结果可能反映了4例患者(3期和4期)就诊时已处于晚期,而非治疗延迟,而2例早期癌症(1期和2期)患者治疗延迟导致分娩后病情进展到更晚期。

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