[孕期对低分子肝素皮肤过敏的女性使用达那肝素进行治疗]

[[Treatment with danaparoid during pregnancy for a woman with a cutenous allergy to low-molecular-weight heparin] ].

作者信息

de Saint-Blanquat L, Simon L, Toubas M F, Hamza J

机构信息

Service d'anesthésie-réanimation chirurgicale, hôpital Saint-Vincent-de-Paul, 74-82, avenue Denfert-Rochereau, 75014 Paris, France.

出版信息

Ann Fr Anesth Reanim. 2000 Dec;19(10):751-4. doi: 10.1016/s0750-7658(00)00309-9.

DOI:10.1016/s0750-7658(00)00309-9

PMID:11200764

Abstract

The authors describe a case of heparin-induced skin reaction due to two preparations of low molecular weight heparin in a pregnant woman. The main characteristics of heparin-related cutaneous allergy are reported. The use of an heparinoid, usually indicated for patients with heparin-induced thrombocytopenia, appeared to be efficient and safe for the mother and her fetus. An epidural analgesia was performed for labor analgesia, 24 hours after the last injection of danaparid of sodium.

摘要

作者描述了一名孕妇因两种低分子量肝素制剂导致肝素诱导的皮肤反应的病例。报告了肝素相关皮肤过敏的主要特征。对于肝素诱导的血小板减少症患者通常使用的类肝素，对母亲及其胎儿似乎有效且安全。在最后一次注射达那肝素钠24小时后，进行了硬膜外镇痛用于分娩镇痛。