Menezo J L, Peris-Martínez C, Cisneros A, Martínez-Costa R
Department of Surgery, University of Valencia, School of Medicine, Spain.
J Refract Surg. 2001 Jan-Feb;17(1):32-42. doi: 10.3928/1081-597X-20010101-04.
To determine the feasibility of using posterior chamber phakic intraocular lenses (PIOLs) to treat high myopia, comparing two different models, Staar and Adatomed.
Twenty-four eyes from 12 patients were studied prospectively. A phakic Staar IOL was implanted in one eye of each patient, and the other eye received a phakic Adatomed IOL. Patients with uveitis or ocular trauma prior to ocular surgery, diabetic retinopathy, or capsular pseudoexfoliation were excluded. The mean preoperative spherical equivalent refraction was -16.00 +/- 5.05 D for the Staar group and -15.39 +/- 2.83 D for the Adatomed group. Average follow-up was 32.4 months (range, 19 to 46 mo) for the Adatomed group and 18.3 months (range, 11 to 21 mo) for the Staar group and included evaluation of intraocular pressure, intraocular lens pigment deposits, lens decentration, anterior subcapsular cataract, and visual acuity.
Spectacle-corrected and uncorrected visual acuity improved in all eyes in both groups. No statistically significant differences in visual acuity gain were observed with the two materials (Student t-test, P = .08 for the Staar group and P = .6 for the Adatomed group), although the gain in visual acuity was somewhat greater with the Staar PIOLs. The difference in mean intraocular pressure before surgery and at last follow-up was 1.5 mmHg for the Staar group and 2.3 mmHg for the Adatomed group (P = .36). The incidence of lens pigment deposits was the same in both groups (41.66%), with deposits in 5 of the 12 eyes in both groups. The incidence of lens decentration was higher in the Adatomed group (5/12; 41.66%) than in the Staar group (2/12; 16.7%). Anterior subcapsular cataract was higher in the Adatomed group (4/12; 33.3%) than in the Staar group (3/12; 25%).
There was a higher incidence of lens decentration and anterior subcapsular cataract in the Adatomed group than in the Staar group.
比较两种不同型号（Staar和Adatomed）的后房型有晶状体眼人工晶状体（PIOL）治疗高度近视的可行性。
对12例患者的24只眼进行前瞻性研究。为每位患者的一只眼植入Staar有晶状体眼人工晶状体，另一只眼植入Adatomed有晶状体眼人工晶状体。排除眼部手术前有葡萄膜炎或眼外伤、糖尿病视网膜病变或晶状体囊假性剥脱的患者。Staar组术前平均等效球镜度为-16.00±5.05D，Adatomed组为-15.39±2.83D。Adatomed组平均随访32.4个月（范围19至46个月），Staar组平均随访18.3个月（范围11至21个月），随访内容包括眼压、人工晶状体色素沉着、晶状体偏心、前囊下白内障和视力评估。
两组所有眼的矫正视力和未矫正视力均有改善。两种材料的视力提高无统计学显著差异（Student t检验，Staar组P = 0.08，Adatomed组P = 0.6），尽管Staar有晶状体眼人工晶状体的视力提高幅度稍大。Staar组手术前与最后一次随访时的平均眼压差值为1.5mmHg，Adatomed组为2.3mmHg（P = 0.36）。两组晶状体色素沉着发生率相同（41.66%），两组12只眼中均有5只眼出现色素沉着。Adatomed组晶状体偏心发生率（5/12；41.66%）高于Staar组（2/12；16.7%）。Adatomed组前囊下白内障发生率（4/12；33.3%）高于Staar组（3/12；25%）。
Adatomed组晶状体偏心和前囊下白内障的发生率高于Staar组。
