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间歇性跌倒和大便失禁作为儿童特发性部分性癫痫中癫痫性负性肌阵挛的一种表现。

Intermittent falls and fecal incontinence as a manifestation of epileptic negative myoclonus in idiopathic partial epilepsy of childhood.

作者信息

Capovilla G, Rubboli G, Beccaria F, Meregalli S, Veggiotti P, Giambelli P M, Meletti S, Tassinari C A

机构信息

Department of Child Neuropsychiatry, C. Poma Hospital, Mantova, Italy.

出版信息

Neuropediatrics. 2000 Oct;31(5):273-5. doi: 10.1055/s-2000-9237.

Abstract

We report two children, suffering from idiopathic partial epilepsy, who started to present, in the same period of time, with epileptic negative myoclonus (ENM) in one lower limb and fecal incontinence (FI). Polygraphic recordings showed that ENM was associated with paroxysmal activities distributed over the vertex region. Both ENM and FI disappeared when ethosuximide treatment was started. We hypothesize that, in our patients, ENM in one lower limb and FI depended on a transitory impairment, caused by epileptic activity that altered the functionality of nearby cortical areas, located in fronto-mesial regions, involved in the control of the muscular tone of the lower limbs and of the pelvic floor muscles.

摘要

我们报告了两名患有特发性部分性癫痫的儿童,他们在同一时期开始出现一侧下肢的癫痫性负性肌阵挛(ENM)和大便失禁(FI)。多导记录显示,ENM与分布于头顶区域的阵发性活动相关。开始使用乙琥胺治疗后,ENM和FI均消失。我们推测,在我们的患者中,一侧下肢的ENM和FI取决于一种短暂性损害,该损害由癫痫活动引起,改变了位于额内侧区域、参与控制下肢和盆底肌肉肌张力的附近皮质区域的功能。

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