Filippi M
Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan, Italy.
Neurol Sci. 2000;21(4 Suppl 2):S877-81. doi: 10.1007/s100720070030.
Conventional magnetic resonance imaging (MRI) has markedly increased our ability to detect the macroscopic abnormalities of the brain and spinal cord in patients with multiple sclerosis (MS). Magnetization transfer imaging and diffusion-weighted imaging have the potential to provide relevant and complementary information on the structural changes occurring within and outside these lesions and are contributing significantly to our understanding of the mechanisms leading to the accumulation of irreversible neurological disability in MS patients. The present review will summarize the major results achieved with the application of these two MR techniques to the assessment of the evolution of MS.
传统磁共振成像（MRI）显著提高了我们检测多发性硬化症（MS）患者脑和脊髓宏观异常的能力。磁化传递成像和扩散加权成像有可能提供有关这些病变内外发生的结构变化的相关且互补的信息，并对我们理解导致MS患者出现不可逆神经功能残疾累积的机制做出了重大贡献。本综述将总结应用这两种磁共振技术评估MS病情进展所取得的主要成果。
