Mauriño J, Saposnik G, Franco A, Lepera S, Rey R C, Sica R E
División de Neurología, Hospital JM Ramos Mejía, Buenos Aires, Argentina.
Rev Neurol. 2000;31(12):1165-7.
Bilateral paramedian thalamic infarcts are uncommon. The most frequent clinical manifestations are acute impairment of consciousness, oculomotor abnormalities and cognitive disturbances. A fluctuating course has not been previously reported.
A 66 year-old woman with a past history of arterial hypertension and diabetes was admitted to our hospital presenting four episodes of decreased consciousness and vertical gaze paresis. Neurological examination between episodes was unremarkable. Diffusion-weighted magnetic resonance imaging revealed high-signal lesions in both paramedian thalamic areas.
Fluctuating impairment of consciousness may be a clinical presentation of bilateral paramedian thalamic infarction. Atheromatous occlusion of the mouth of the paramedian thalamic penetrating artery is the most common cause. Neurological findings and diffusion-weighted images may help to define the extension and the underlying pathophysiological mechanism.
双侧丘脑旁正中梗死并不常见。最常见的临床表现为急性意识障碍、动眼异常和认知障碍。此前尚未有病情波动病程的报道。
一名66岁女性,有动脉高血压和糖尿病病史,因出现4次意识减退和垂直凝视麻痹发作入住我院。发作间期的神经学检查无异常。弥散加权磁共振成像显示双侧丘脑旁正中区域有高信号病变。
意识波动障碍可能是双侧丘脑旁正中梗死的一种临床表现。丘脑旁正中穿通动脉开口处的动脉粥样硬化闭塞是最常见的病因。神经学检查结果和弥散加权图像可能有助于明确病变范围及潜在的病理生理机制。