特发性血小板减少性紫癜与麻疹、腮腺炎、风疹联合疫苗
Idiopathic thrombocytopenic purpura and MMR vaccine.
作者信息
Miller E, Waight P, Farrington C P, Andrews N, Stowe J, Taylor B
机构信息
Immunisation Division, Public Health Laboratory Service Communicable Disease Surveillance Centre, Colindale, London NW9 5EQ, UK.
出版信息
Arch Dis Child. 2001 Mar;84(3):227-9. doi: 10.1136/adc.84.3.227.
Abstract
A CAUSAL ASSOCIATION BETWEEN MEASLES
mumps-rubella (MMR) vaccine and idiopathic thrombocytopenic purpura (ITP) was confirmed using immunisation/hospital admission record linkage. The absolute risk within six weeks of immunisation was 1 in 22 300 doses, with two of every three cases occurring in the six week post-immunisation period being caused by MMR. Children with ITP before MMR had no vaccine associated recurrences.
摘要
通过免疫接种/住院记录联动，证实了麻疹-腮腺炎-风疹（MMR）疫苗与特发性血小板减少性紫癜（ITP）之间存在因果关联。免疫接种后六周内的绝对风险为每22300剂中有1例，每三例病例中有两例发生在免疫接种后的六周内，是由MMR疫苗引起的。接种MMR疫苗前患有ITP的儿童没有与疫苗相关的复发情况。
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