Freeman T W, Kimbrell T
University of Arkansas Medical Sciences, Department of Psychiatry, Central Arkansas Veterans Healthcare System, Little Rock, Arkansas, USA.
J Neuropsychiatry Clin Neurosci. 2001 Winter;13(1):106-9. doi: 10.1176/jnp.13.1.106.
A 48-year-old combat veteran sustained a right frontal cerebral infarct at the age of 45 years. The patient's family reports that prior to the infarct he had a preoccupation with memories of combat, as well as nightmares, avoidance of reminders, and multiple arousal symptoms. Since his recovery from the infarct, the patient and his family continue to relate significant arousal symptoms but deny any continued history of preoccupation with traumatic memories, reminder avoidance, or nightmares. The resolution of a limited number of symptoms in this patient following damage to the right frontal cortex suggests that some of the symptoms of posttraumatic stress disorder may be amenable to current biological interventions.
一名48岁的退伍军人在45岁时右侧额叶发生脑梗死。患者家属报告称,在梗死之前,他一直沉迷于战斗记忆,还伴有噩梦、回避提示物以及多种觉醒症状。自从从梗死中康复后,患者及其家属仍有明显的觉醒症状,但否认有持续沉迷于创伤性记忆、回避提示物或做噩梦的情况。该患者右侧额叶皮质受损后部分症状得到缓解,这表明创伤后应激障碍的某些症状可能适合目前的生物干预措施。