Koumantaki E, Georgala S, Rallis E, Papadavid E
Department of Dermatology, A. Syggros Hospital, Athens, Greece.
Pediatr Dermatol. 2001 Jan-Feb;18(1):60-2. doi: 10.1046/j.1525-1470.2001.018001060.x.
We report an 8-month-old girl with tinea capitis caused by Microsporum canis which was successfully treated with two pulses of oral itraconazole 50 mg/day, each of 1 week duration with an interval of 2 weeks. M. canis tinea capitis can be a difficult therapeutic problem in an infant, as the treatment is usually long, lasting up to 4-6 weeks with griseofulvin and 6-12 weeks with terbinafine, and the desire to provide a safe systemic therapy is particularly important. With an intermittent regimen the duration of treatment with active drug can be much shorter compared to continuous therapy. We found that itraconazole pulse therapy for M. canis tinea capitis was a safe and effective treatment in an infant.
我们报告了一名8个月大的女童,她患有犬小孢子菌引起的头癣,通过口服伊曲康唑50毫克/天,分两个疗程成功治愈,每个疗程持续1周,间隔2周。犬小孢子菌头癣在婴儿中可能是一个治疗难题,因为通常治疗时间较长,灰黄霉素治疗长达4 - 6周,特比萘芬治疗长达6 - 12周,因此提供安全的全身治疗尤为重要。与持续治疗相比,间歇疗法使用活性药物的治疗时间可以短得多。我们发现伊曲康唑脉冲疗法治疗婴儿犬小孢子菌头癣是一种安全有效的治疗方法。