Łangowska-Adamczyk H, Jedrusik-Pawłowska M
Department of Maxillofacial Surgery, Silesian Medical University, ul. Francuska 20/27, 40-027 Katowice, Poland.
Med Sci Monit. 2000 Nov-Dec;6(6):1174-8.
Langerhans cell histiocytosis (LCH) is a disease involving formation of granulomatous infiltrations consisting of Langerhans cells, histiocytes, lymphocytes and eosinophilic granulocytes. Etiopathogenesis of this disease has not been fully clarified yet. It can present as a focal and disseminated form (acute and chronic). Rare incidence of this disease in the population causes progress in research and new therapeutic methods to be slow. Basing upon a case of a patient treated for gingivo-osseous lesions in the course of LCH, we tried to prove that a dental or maxillofacial surgeon may be the first contact medical professional who contributes to the diagnosis of LCH as a systemic disease.
朗格汉斯细胞组织细胞增多症（LCH）是一种涉及由朗格汉斯细胞、组织细胞、淋巴细胞和嗜酸性粒细胞组成的肉芽肿性浸润形成的疾病。该疾病的病因发病机制尚未完全阐明。它可表现为局灶性和播散性形式（急性和慢性）。该疾病在人群中的发病率较低，导致研究进展和新治疗方法的发展缓慢。基于一例在LCH病程中接受牙龈骨病变治疗的患者病例，我们试图证明牙科或颌面外科医生可能是有助于将LCH诊断为全身性疾病的首个接触医疗专业人员。
