Blonsky E R, Logemann J A, Boshes B, Fisher H B
J Gerontol. 1975 May;30(3):299-303. doi: 10.1093/geronj/30.3.299.
In a study of vocal tract and esophageal function during speech and swallowing, unmedicated Parkinson patients were found to have specific disorders in oral and esophageal stages of deglutition and a predictable sequence of deterioration in speech. To determine whether these disorders are exclusive to parkinsonism or are typical of all patients with tremor or of geriatric patients in general, a cinefluoroscopic study was initiated to examine the physiology of speech and swallowing in these other patients. Subjects were 10 normal geriatric patients and 10 patients with essential tremor. Results of the studies for these two groups were compared with data from earlier studies on unmedicated Parkinson patients. Parkinson patients showed most severely disordered swallowing and speech function. Patients with essential tremor showed only slight slowing in esophageal transit during swallowing and vocal tremor during speech, but no progressive deterioration. Normal geriatric patients revealed no swallowing or speech disturbances.
在一项关于言语和吞咽过程中声道及食管功能的研究中，发现未用药的帕金森病患者在吞咽的口腔期和食管期存在特定紊乱，且言语功能有可预测的恶化顺序。为了确定这些紊乱是否为帕金森病所特有，还是所有震颤患者或一般老年患者的典型特征，启动了一项荧光透视电影研究，以检查其他这些患者的言语和吞咽生理功能。研究对象为10名正常老年患者和10名特发性震颤患者。将这两组的研究结果与早期关于未用药帕金森病患者的研究数据进行了比较。帕金森病患者的吞咽和言语功能紊乱最为严重。特发性震颤患者在吞咽时仅食管通过略有减慢，言语时有声音震颤，但无进行性恶化。正常老年患者未出现吞咽或言语障碍。
