Transmitochondrial mice: proof of principle and promises.
作者信息
Hirano M
机构信息
Department of Neurology, Columbia-Presbyterian Medical Center, 630 West 168th Street, P&S 4-443, New York, NY 10032, USA.
出版信息
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):401-3. doi: 10.1073/pnas.98.2.401.
Abstract
摘要
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本文引用的文献
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Maternal germ-line transmission of mutant mtDNAs from embryonic stem cell-derived chimeric mice.来自胚胎干细胞衍生嵌合小鼠的突变线粒体DNA的母系生殖系传递。
Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14461-6. doi: 10.1073/pnas.250491597.
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Generation of mice with mitochondrial dysfunction by introducing mouse mtDNA carrying a deletion into zygotes.通过将携带缺失的小鼠线粒体DNA导入受精卵来生成线粒体功能障碍的小鼠。
Nat Genet. 2000 Oct;26(2):176-81. doi: 10.1038/82826.
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A debut for mito-mouse.线粒体小鼠首次亮相。
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Mutations in mtDNA: are we scraping the bottom of the barrel?线粒体DNA突变：我们是否已触及底线？
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Transmitochondrial mice carrying resistance to chloramphenicol on mitochondrial DNA: developing the first mouse model of mitochondrial DNA disease.线粒体DNA携带氯霉素抗性的转线粒体小鼠：开发首个线粒体DNA疾病小鼠模型。
Nat Med. 1999 Aug;5(8):957-60. doi: 10.1038/11403.
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Mitochondrial diseases in man and mouse.人类和小鼠的线粒体疾病。
Science. 1999 Mar 5;283(5407):1482-8. doi: 10.1126/science.283.5407.1482.
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Maternally inherited cardiomyopathy: an atypical presentation of the mtDNA 12S rRNA gene A1555G mutation.母系遗传的心肌病：线粒体DNA 12S rRNA基因A1555G突变的非典型表现。
Am J Hum Genet. 1999 Jan;64(1):295-300. doi: 10.1086/302188.
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Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice.线粒体转录因子A对小鼠的线粒体DNA维持和胚胎发育至关重要。
Nat Genet. 1998 Mar;18(3):231-6. doi: 10.1038/ng0398-231.
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Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice.异质性小鼠中不同线粒体DNA基因型的组织特异性选择
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