Brown W V
Division of Arteriosclerosis and Lipid Metabolism, Atlanta Veterans Affairs Medical Center, 1670 Clairmont Road, Decatur, GA 30033, USA.
Diabetes Obes Metab. 2000 Nov;2 Suppl 2:S11-8. doi: 10.1046/j.1463-1326.2000.00001.x.
The risks of cardiovascular and cerebrovascular disease in patients with diabetes are greater than those in persons without diabetes. This is due, in part, to the metabolic effects of insulin resistance. Other contributing factors include hyperglycaemia, dyslipidaemia, hypertension, hypercoagulability, homocysteinaemia, smoking, and obesity. Risk factor modification, where possible, can reduce the risk of complications of diabetes and macrovascular disease.
糖尿病患者发生心血管疾病的风险高于非糖尿病患者。这部分归因于胰岛素抵抗的代谢效应。其他促成因素包括高血糖、血脂异常、高血压、高凝状态、高同型半胱氨酸血症、吸烟和肥胖。尽可能改变危险因素可降低糖尿病和大血管疾病并发症的风险。
