Mel'nik G V, Degtiar' L D
Klin Med (Mosk). 2000;78(12):40-3.
Icterohemorrhagic spirochetosis convalescents develop slowly regressing renal dysfunctions most frequent of which are chronic renal failure, pyelonephritis and tubulointersticial nephritis, arterial hypertension. Renal disorders may be due to immunopathological reactions followed by activation of bacterial microflora. Damage from commissures at the sites of prior hemorrhage is also possible. In bovine leptospirosis renal damage is not so severe but it tends to progression. So, renal affection in leptospirosis is a specific pathology observed in any clinical form of the disease and demands surveillance in the regions of local focuses.
出血性黄疸型钩端螺旋体病康复者会出现缓慢消退的肾功能障碍,其中最常见的是慢性肾衰竭、肾盂肾炎、肾小管间质性肾炎和动脉高血压。肾脏疾病可能是由于免疫病理反应继发细菌菌群激活所致。先前出血部位的粘连损伤也有可能。在牛钩端螺旋体病中,肾脏损伤没那么严重,但有进展趋势。因此,钩端螺旋体病中的肾脏病变是该疾病任何临床形式中都观察到的一种特殊病理情况,在局部疫源地地区需要进行监测。