[Inguinal lymph nodes of Rhesus macaque in hypokinesia and combined action of hypokinesia and hypergravity].

Peculiarities of microanatomy and cytoarchitecture of inguinal lymph nodes were studied under the effect of hypokinezia and combined effect of hypokinezia and hypergravitation experimentally in mature macaque rhesus monkeys for the first time. The data obtained indicate that on the background of intensive impairing effect of hypokinezia combined action was not only neutralized but the effect of hypokinezia also intensifies immunological action of lymph nodes of monkeys. This was supported by morphological signs and changes in correlation between lymphoid cells: number growth of lymphoid nodules with widened germinal centres and high fraction of mitotically dividing cells, the presence of dense thymus dependent (paracortical) zone and more dense medullar bands, filled basically with small lymphocytes and lowered level of destructive processes in all structural components of lymph nodes.