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非允许系统中诱导增殖的病毒作为人类癌症的可能病因

Proliferation-inducing viruses in non-permissive systems as possible causes of human cancers.

作者信息

zur Hausen H

机构信息

Deutsches Krebsforschungzentrum, Heidelberg, Germany.

出版信息

Lancet. 2001 Feb 3;357(9253):381-4. doi: 10.1016/S0140-6736(00)03652-7.

Abstract

Animal viruses, some of which are probably unable to replicate in human cells, could be transmitted to people where they may be linked to tumours currently not attributed to viruses. Several human virus types have oncogenic potential in animals. A potential risk for acquiring such infections by handling and preparation of animal products was analysed against the background of available epidemiological reports. Human tumours should be systematically assessed for proliferation-inducing viruses in non-permissive systems.

摘要

动物病毒,其中一些可能无法在人类细胞中复制,可传播给人类,在人类中它们可能与目前未归因于病毒的肿瘤有关。几种人类病毒类型在动物中具有致癌潜力。根据现有流行病学报告,分析了通过处理和制备动物产品而感染此类病毒的潜在风险。应在非允许系统中对人类肿瘤进行系统性评估,以检测是否存在诱导增殖的病毒。

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