Shawker T H, Dunnick N R, Head G L, Magrath I T
J Clin Ultrasound. 1979 Aug;7(4):279-83. doi: 10.1002/jcu.1870070408.
Burkitt's lymphoma is a childhood disease that characteristically produces large, bulky abdominal tumors. Although these are potentially curable, chemotherapy can produce rapid tumor lysis, with subsequent life-threatening metabolic abnormalities, especially in those patients with large tumors or those who have compromised renal function. Twenty-two patients with proven Burkitt's lymphoma were evaluated by ultrasound. Thirteen patients had abdominal masses. These masses tended to be large, solitary, and acoustically homogeneous. Although most of these tumors were found in the pelvis, upper abdominal and retroperitoneal tumors were also encountered. None of the patients had the typical paravertebral mantle of enlarged nodes seen in other types of lymphoma. In 11 patients with abnormal intravenous pyelograms, ultrasound successfully distinguished between renal lymphoma, hydronephrosis, and, by exclusion, metabolic renal disease. The absence of lymph node disease and the presence of bulky homogeneous extranodal tumor are characteristic ultrasound findings in Burkitt's lymphoma. By locating and quantifying tumor mass and distinguishing between renal lymphoma and hydronephrosis, ultrasound proved to be clinically useful in the management of this disease.
伯基特淋巴瘤是一种儿童疾病，其特征是会产生巨大的腹部肿块。尽管这些肿瘤有潜在的治愈可能，但化疗会导致肿瘤迅速溶解，继而引发危及生命的代谢异常，尤其是在那些患有大肿瘤或肾功能不全的患者中。对22例经证实的伯基特淋巴瘤患者进行了超声检查。13例患者有腹部肿块。这些肿块往往较大、孤立且回声均匀。尽管这些肿瘤大多位于盆腔，但也发现了上腹部和腹膜后肿瘤。没有患者出现其他类型淋巴瘤中常见的典型椎旁肿大淋巴结套。在11例静脉肾盂造影异常的患者中，超声成功区分了肾淋巴瘤、肾积水，并通过排除法鉴别了代谢性肾病。无淋巴结病变以及存在巨大均匀的结外肿瘤是伯基特淋巴瘤典型的超声表现。通过定位和量化肿瘤肿块以及区分肾淋巴瘤和肾积水，超声在该疾病的治疗中被证明具有临床实用性。
