一只犬因内脏肥大细胞瘤继发腹腔积液。病例报告。
Peritoneal effusion in a dog secondary to visceral mast cell tumor. A case report.
作者信息
de Souza M L, Torres L F, Rocha N S, Takahira R K, Mamprim M J, Burini C H, Bandarra E P, Figueiredo L M
机构信息
Departments of Clinics and of Animal Reproduction and Radiology, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
出版信息
Acta Cytol. 2001 Jan-Feb;45(1):89-92. doi: 10.1159/000327194.
BACKGROUND
Mast cell tumor, one of the most common skin tumors in dogs, may also be found in visceral sites (mainly spleen and liver). When a visceral mast cell tumor is present, neoplastic mast cells may be found in any effusion secondary to the tumor. Therefore, the diagnosis may be made by cytologic analysis of the effusion.
CASE
An 8-year-old, spayed, female Siberian husky presented with a peritoneal effusion secondary to a visceral mast cell tumor. Seven months earlier, the dog had presented with a cutaneous nodule diagnosed as a well-differentiated mast cell tumor. The peritoneal fluid was classified as a transudate. Numerous neoplastic mast cells were found in the effusion. Although the mast cell tumor presented with characteristics of the well-differentiated tumor, its biologic behavior was that of a malignant tumor.
CONCLUSION
Care should be taken to evaluate the prognosis of mast cell tumors in dogs since their biologic behavior is extremely variable.
背景
肥大细胞瘤是犬类最常见的皮肤肿瘤之一，也可能出现在内脏部位（主要是脾脏和肝脏）。当存在内脏肥大细胞瘤时，在肿瘤继发的任何积液中都可能发现肿瘤性肥大细胞。因此，可通过积液的细胞学分析做出诊断。
病例
一只8岁已绝育的雌性西伯利亚哈士奇因内脏肥大细胞瘤继发腹腔积液前来就诊。7个月前，这只狗出现一个皮肤结节，诊断为高分化肥大细胞瘤。腹腔积液被分类为漏出液。在积液中发现了大量肿瘤性肥大细胞。尽管肥大细胞瘤表现出高分化肿瘤的特征，但其生物学行为却是恶性肿瘤的行为。
结论
由于犬肥大细胞瘤的生物学行为变化极大，因此在评估其预后时应谨慎。
Zotero 插件