Balint B, Jovicić A, Apostolski S, Magdić B, Taseski J
Military Medical Academy, Institute of Transfusiology, Belgrade.
Vojnosanit Pregl. 2000 Sep-Oct;57(5):11-5.
During the last twenty-year period therapeutic plasma exchange (TPE) was used in the treatment of 68 patients with myasthenia gravis and 61 patients with multiple sclerosis. The therapeutic effects were evaluated on the basis of neurologic deficit changes, electrophysiological findings, necessary laboratory analyses and patient's general conditions. It was shown that the therapeutic effects mosty depended on the nature and stage of the basic disease, adequate selection of the patients and timely applied therapeutic procedure. Significant positive effects of the TPE treatment applied with the anti-inflammatory and immunosuppressive therapy were observed in patients with myasthenia gravis and multiple sclerosis upon clinical findings and some paraclinical tests.
在过去的二十年里，治疗性血浆置换（TPE）被用于治疗68例重症肌无力患者和61例多发性硬化症患者。根据神经功能缺损变化、电生理检查结果、必要的实验室分析以及患者的一般状况对治疗效果进行评估。结果表明，治疗效果主要取决于基础疾病的性质和阶段、患者的适当选择以及及时应用的治疗程序。在重症肌无力和多发性硬化症患者中，结合抗炎和免疫抑制疗法应用TPE治疗，在临床检查结果和一些辅助检查中观察到了显著的积极效果。
