Nevitt P C, Das Narla L, Hingsbergen E A
Medical College of Virginia, Virginia Commonwealth University, Department of Radiology, Richmond 23298-0615, USA.
Pediatr Radiol. 2001 Feb;31(2):115-6. doi: 10.1007/s002470000383.
Mucormycosis is an uncommon and frequently fatal fungal infection. It characteristically affects patients with diabetes mellitus or patients with severe immunosuppression. The hallmark of mucormycosis infection is tissue infarction and vascular invasion. We present clinical data and imaging studies of a 16 year-old child with acute lymphoblastic leukemia complicated by disseminated mucormycosis resulting in a pseudoaneurysm of the spleen. This was successfully managed by a combination of systemic antifungal therapy (Amphotericin B) and surgery (splenectomy). This entity has not been described in the literature.
毛霉菌病是一种罕见且常致命的真菌感染。它典型地影响糖尿病患者或严重免疫抑制患者。毛霉菌病感染的标志是组织梗死和血管侵袭。我们展示了一名16岁急性淋巴细胞白血病合并播散性毛霉菌病导致脾假性动脉瘤患儿的临床资料和影像学研究。通过全身性抗真菌治疗(两性霉素B)和手术(脾切除术)联合成功治疗了该病例。文献中尚未描述过这种情况。