Gorby W G, Martin W G
Proc Soc Exp Biol Med. 1975 Feb;148(2):544-9. doi: 10.3181/00379727-148-38580.
The in vitro and in vivo influence of K+ on the activity of rat heart and liver PAPS-sulfotransferase (P1) was tested. The P1 activity was optimal with 0.5 mumoles K+ per mug protein. The P1 activity was decreased by mild dialysis and lost by extended dialysis. The enzyme was stable when dialyzed with K+ and tests with other ions indicated K+ specificity. Rats fed purified diets with low, normal or high levels of K+ had significantly different heart taurine concentrations and P1 specific activities. These P1 specific activities became comparable to those from the rats receiving the normal K+ diet by the addition of KCl to the assay mixture.