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[采用靶控输注和脑电双频指数的微创冠状动脉搭桥术的麻醉管理]

[Anesthetic management for MIDCAB using the target controlled infusion and the bispectral index].

作者信息

Satoh M, Chinzei M, Nagata O, Kawashima Y, Hanaoka K

机构信息

Department of Anesthesiology and Pain Relief Center, University of Tokyo Hospital, Tokyo 113-8655.

出版信息

Masui. 2000 Nov;49(11):1257-60.

Abstract

We report our experience in using the target controlled infusion (TCI) of propofol combined with the bispectral index (BIS) monitoring for anesthetic management of minimally invasive direct coronary artery bypass (MIDCAB) in a 43-year-old-male patient with angina pectoris. After premedication, the patient was connected to the monitor with electrodes for BIS monitor. Then, anesthesia was induced with fentanyl and propofol using TCI technique. When blood concentration of propofol reached 4 micrograms.ml-1, the trachea was intubated. Before starting the operation, we evaluated the relationship between blood concentration of propofol and the value of BIS, and the standard maintenance concentration of propofol was set at 3 micrograms.ml-1. When the concentration of propofol was 3 micrograms.ml-1, the value of BIS was about 60. Anesthesia was maintained with nitrous oxide and oxygen and continuous infusion of propofol using TCI technique. When necessary, we gave additional injection of fentanyl and vecuronium bromide. Furthermore, diltiazem was infused continuously for cardiac rate control, as well as infusion of nicorandil, nitroglycerine for prevention of coronary artery spasms, and prostaglandin. After the operation, the patient was alert in 8 minutes and we could extubate in 12 minutes. The use of TCI combined with BIS monitoring for maintenance of anesthesia for MIDCAB is useful and safe.

摘要

我们报告了在一名43岁心绞痛男性患者的微创直接冠状动脉旁路移植术(MIDCAB)麻醉管理中,使用丙泊酚靶控输注(TCI)联合脑电双频指数(BIS)监测的经验。术前用药后,患者连接带有电极的监测仪以进行BIS监测。然后,采用TCI技术用芬太尼和丙泊酚诱导麻醉。当丙泊酚血药浓度达到4微克/毫升时,进行气管插管。在开始手术前,我们评估了丙泊酚血药浓度与BIS值之间的关系,并将丙泊酚的标准维持浓度设定为3微克/毫升。当丙泊酚浓度为3微克/毫升时,BIS值约为60。使用氧化亚氮和氧气并采用TCI技术持续输注丙泊酚维持麻醉。必要时,额外注射芬太尼和维库溴铵。此外,持续输注地尔硫卓以控制心率,以及输注尼可地尔、硝酸甘油以预防冠状动脉痉挛,并输注前列腺素。术后,患者在8分钟后清醒,12分钟后可拔除气管导管。对于MIDCAB麻醉维持,TCI联合BIS监测的使用是有用且安全的。

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