Urayama O, Chihara J
Kawai Clinic, Tsukuba 305-0812.
Rinsho Byori. 2000 Dec;48(12):1136-41.
The incidence of lung cancer is increasing in Japan and it is important to know whether a patient has a history of primary smoking/second-hand smoking because smoking is the main cause of lung cancer. Lung cancer is often found on chest roentgenography. In order to determine the strategy of the treatment, the stage of the disease can be studied by the examinations of morphology(chest computed tomography), pathology(biopsy under bronchoscopy) and biochemistry(tumor markers and genetic analysis). Most lung cancers are detected in the advanced stage with metastasis. Performance status should be useful for the estimation of the prognosis of patients. In the symposium, we reported two of our clinical cases, in which urinary deoxypyridinoline, a bone absorption marker, facilitated the discovery of the bone metastasis of lung cancers with negative bone scans. We were requested to verify the early diagnosis of lung cancers with a collection of data on morphology, pathology and biochemistry.
在日本，肺癌的发病率正在上升，了解患者是否有原发性吸烟/二手烟史很重要，因为吸烟是肺癌的主要病因。肺癌常在胸部X线检查中被发现。为了确定治疗策略，可以通过形态学检查（胸部计算机断层扫描）、病理学检查（支气管镜下活检）和生物化学检查（肿瘤标志物和基因分析）来研究疾病的分期。大多数肺癌在出现转移的晚期被发现。体能状态对于评估患者的预后应该是有用的。在研讨会上，我们报告了两例临床病例，其中骨吸收标志物尿脱氧吡啶啉有助于发现骨扫描阴性的肺癌骨转移。我们被要求通过收集形态学、病理学和生物化学方面的数据来验证肺癌的早期诊断。
