Leszczyńska-Gorzelak B, Szymczyk G, Oleszczuk J J
Kliniki Połoznictwa i Perinatologii II Katedry Połoznictwa i Chorób Kobiecych Akademii Medycznej w Lublinie.
Ginekol Pol. 2000 Nov;71(11):1422-8.
Preeclampsia is a pregnancy-specific disorder of humans which rates among one of the major cases of maternal and fetal morbidity and mortality. Etiology of preeclampsia is still largely unraveled and treatment is syndrome specific.
Evaluation of the incidence of preeclampsia in twin pregnancies and comparison of selected clinical characteristics among preeclamptic and non-preeclamptic twin pregnancy patients.
Retrospective analysis of 194 normotensive and 25 preeclamptic patients with twin pregnancies admitted to the Lublin State Hospital Nr 4 between January 1st 1992 and December 31st 1997. Patients were matched for gravidity, parity, maternal age and selected biochemical parameters.
Preeclampsia occurred two times more frequently in nulliparous women (68% vs 32%). Gravidas with preeclampsia had significantly higher serum uric acid levels than their non-preeclamptic counterparts (6.7 +/- 0.3 vs 4.3 +/- 0.1; p < 0.001). Hypertension, proteinuria and edema coexisted concomitantly in 52% of preeclamptic patients.
子痫前期是人类妊娠期特有的一种疾病，是孕产妇和胎儿发病及死亡的主要原因之一。子痫前期的病因仍大多未明，治疗是针对综合征的。
评估双胎妊娠子痫前期的发病率，并比较子痫前期和非子痫前期双胎妊娠患者的某些临床特征。
对1992年1月1日至1997年12月31日期间入住卢布林市第4国立医院的194例血压正常的双胎妊娠患者和25例子痫前期双胎妊娠患者进行回顾性分析。患者在妊娠次数、产次、产妇年龄和某些生化参数方面进行了匹配。
初产妇子痫前期的发生率高出两倍（68%对32%）。子痫前期孕妇的血清尿酸水平显著高于非子痫前期孕妇（6.7±0.3对4.3±0.1；p<0.001）。52%的子痫前期患者同时存在高血压、蛋白尿和水肿。
