Szymula D, Leszczyńska-Gorzelak B, Marciniak B, Oleszczuk J
Kliniki Poloznictwa i Perinatologii Akademii Medycznej w Lublinie.
Ginekol Pol. 2000 Nov;71(11):1469-75.
There are some unique problems of prenatal diagnosis and genetic counselling of twins, although methods of evaluation are similar in multiply and singleton pregnancies. Indications, risk and complications of this techniques were described. Also sensitivity and specificity of biochemic screening examination were compared between singleton and multiply pregnancy. Prenatal diagnosis based on amniopunction and chorionbiopsy seems to be safe and useful method determining aneuploidy. The risk of this methods is higher in twins than in singleton pregnancies. Although, in twin pregnancies, it is related rather to higher complications rate, than to procedures pregnancies losses.
双胞胎的产前诊断和遗传咨询存在一些独特的问题，尽管多胎妊娠和单胎妊娠的评估方法相似。描述了该技术的适应症、风险和并发症。还比较了单胎妊娠和多胎妊娠生化筛查检查的敏感性和特异性。基于羊膜穿刺术和绒毛取样的产前诊断似乎是确定非整倍体的安全且有用的方法。该方法在双胞胎中的风险高于单胎妊娠。不过，在双胎妊娠中，这更多与较高的并发症发生率有关，而非与手术导致的妊娠丢失有关。
