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非体外循环冠状动脉搭桥手术会增加急性升主动脉夹层的发生率吗?

Increased incidence of acute ascending aortic dissection with off-pump aortocoronary bypass surgery?

作者信息

Chavanon O, Carrier M, Cartier R, Hébert Y, Pellerin M, Pagé P, Perrault L P

机构信息

Department of Surgery, Research Center, Montreal Heart Institute, Quebec, Canada.

出版信息

Ann Thorac Surg. 2001 Jan;71(1):117-21. doi: 10.1016/s0003-4975(00)02136-6.

Abstract

BACKGROUND

An apparent increase in the incidence of acute ascending aortic dissection following off-pump coronary artery bypass grafting (OPCAB) led us to assess retrospectively the rate and circumstances of this complication in our institution on a consecutive series of patients undergoing aortocoronary bypass performed with and without extracorporeal circulation (ECC).

METHODS

A retrospective analysis of acute ascending aortic dissections complicating coronary artery bypass grafting surgery in 3,031 patients in our institution since April 1, 1995, was performed using the database of the Montreal Heart Institute.

RESULTS

There was a greater frequency of hypertension in the OPCAB group. Iatrogenic acute aortic dissection occurred in 3 patients among 308 operated on without ECC (0.97%) and 1 patient among 2,723 operated on under ECC (0.04%). This difference was statistically significant (p < 0.00001).

CONCLUSIONS

The risk of aortic dissection may be increased in OPCAB. Careful manipulation of the aorta with a single side-clamping and a control of the arterial pressure should be used to minimize aortic trauma. High-risk patients should undergo CABG without side-clamping of the aorta or CABG with ECC to prevent this redoubtable complication of myocardial revascularization.

摘要

背景

非体外循环冠状动脉搭桥术(OPCAB)后急性升主动脉夹层发病率明显增加,促使我们对本机构一系列连续接受体外循环(ECC)和非体外循环主动脉冠状动脉搭桥术患者的这一并发症发生率及情况进行回顾性评估。

方法

利用蒙特利尔心脏研究所数据库,对1995年4月1日以来本机构3031例冠状动脉搭桥手术并发急性升主动脉夹层患者进行回顾性分析。

结果

OPCAB组高血压发生率更高。308例非体外循环手术患者中有3例发生医源性急性主动脉夹层(0.97%),2723例体外循环手术患者中有1例发生(0.04%)。这种差异具有统计学意义(p < 0.00001)。

结论

OPCAB中主动脉夹层风险可能增加。应采用单侧夹闭主动脉并仔细操作以及控制动脉压,以尽量减少主动脉创伤。高危患者应行不夹闭主动脉的冠状动脉搭桥术或体外循环冠状动脉搭桥术,以预防这种心肌血运重建的可怕并发症。

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