Pannier J L, Leusen I
Stroke. 1975 Mar-Apr;6(2):188-98. doi: 10.1161/01.str.6.2.188.
Cerebral blood flow was measured with the 133Xenon clearance method in anesthetized cats under controlled ventilation. An acute pressure increase in the carotid system increases the cerebrovascular permeability to Evans blue, indicating damage to the blood-brain barrier. In these conditions the reactivity or cerebral blood vessels toward changes in the acid-base balance is altered: the CO2 reactivity is less pronounced, while the effect of increasing the plasma (HCO-3) is more pronounced than in normal cats. Autoregulatory capacity toward moderate alterations in arterial blood pressure or in intracranial pressure is well maintained in these conditions.
在控制通气的条件下，采用133氙清除法在麻醉猫身上测量脑血流量。颈动脉系统的急性压力升高会增加脑血管对伊文思蓝的通透性，表明血脑屏障受损。在这些情况下，脑血管对酸碱平衡变化的反应性会改变：二氧化碳反应性不那么明显，而血浆（HCO-3）升高的影响比正常猫更明显。在这些情况下，对动脉血压或颅内压适度变化的自动调节能力保持良好。
