Mauri M C, Laini V, Barone R, Clemente A, Volonteri L S, Cerveri G, Steinhilber C, Fornier M
Department of Clinical Psychiatry, University of Milan, Clinical Neuropsychopharmacology Unit, IRCCS Ospedale Maggiore Milano, Guardia 2, Via F. Sforza 35, 20122 Milano, Italy.
Encephale. 2000 Nov-Dec;26(6):21-6.
Forty three patients, mean age 55.20 +/- 9.27 SD, affected by Schizophrenia Residual Type (DSM IV, RDC criteria) and treated with neuroleptic drugs for a mean of 25.42 years (+/- 4.12 SD) were included into the study. Clinical evaluation was cross-sectional assessed by BPRScale, SAPS, SANS, HRS-D, EPSE. ACS and MMSE. Seventy percent of patients presented a "postpsychotic depression" (42%, mild; 16%, moderate and 12% serious). "Postpsychotic depression" does not seem to be influenced by neuroleptics, but it seems to be a component of residual schizophrenia in patients with a long lasting permanence in a mental hospital.