Melián J S, García Nieto V, Sosa A M
Unidad de Pediatría, Centro de Salud de Ofra-Delicias, Santa Cruz de Tenerife.
Nefrologia. 2000 Nov-Dec;20(6):510-6.
The urinary elimination of calcium has been studies in 549 school children from the island of La Gomera (Canary Islands) and in 100 children of a control group from the capital of the Canaries, Santa Cruz de Tenerife. The diet was not manipulated and it was proven that the water that they consumed was of characteristic equal. The 95th centile for the distribution of the calcium/creatinine index was 0.2 in the control group, we calculated the prevalence of hypercalciuria of this group (3.8%) and of the study group (16%). The prevalence was analyzed by areas of the island and it this showed that it was higher (28.4%) in those from isolated communities and therefore, with history of more inbreeding that in those with good communications (10.6%). It was observed that the risk of suffering hypercalciuria among the children that have four grand-parents who are natives of the island of La Gomera is 2.85 times higher than in those that don't have any grand-father/mother coming from the island. Hypercalciuria siblings of children with hypercalciuria found in 50%.
对来自拉戈梅拉岛（加那利群岛）的549名学童以及来自加那利群岛首府圣克鲁斯-德特内里费岛的100名对照组儿童的尿钙排泄情况进行了研究。未对饮食进行控制，且已证实他们所饮用的水具有相同特性。对照组钙/肌酐指数分布的第95百分位数为0.2，我们计算了该组高钙尿症的患病率（3.8%）以及研究组的患病率（16%）。按岛屿区域分析患病率，结果显示来自孤立社区的人群患病率更高（28.4%），因此，与交流良好的人群（10.6%）相比，近亲繁殖历史更长。据观察，祖父母均为拉戈梅拉岛本地人的儿童患高钙尿症的风险比没有任何祖父母来自该岛的儿童高2.85倍。在高钙尿症儿童中，其同胞患高钙尿症的比例为50%。
