非芽孢厌氧菌对十种抗菌药物的体外药敏试验

In vitro susceptibility testing of nonsporing anaerobes to ten antimicrobial agents.

作者信息

Rao P S, Shivananda P G

机构信息

Department of Microbiology, Kasturba Medical College, Manipal.

出版信息

Indian J Pathol Microbiol. 2000 Jul;43(3):281-4.

PMID:11218673

Abstract

Antibiotic susceptibility was performed on sixty clinical isolates of nonsporing anaerobes against ten antimicrobial agents. The test was performed on Muller Hinton Agar and Wilkins Chalgren blood agar by preparing suspension of freshly isolated colonies in BHI broth. Apart from Metronidazole and Chloramphenicol newer antibiotics like Minocycline, Secnidazole, Tinidazole, Clarithromycin, Roxithromycin were also tried. Antimicrobial agents like Metronidazole, Secnidazole, Tinidazole and Minocycline were 100% sensitive, followed by Chloramphenicol, Clarithromycin and Roxithromycin. These newer agents can be good alternatives for the treatment of non sporing anaerobes.

摘要

对60株非芽孢厌氧菌临床分离株进行了针对10种抗菌药物的药敏试验。该试验在Muller Hinton琼脂和Wilkins Chalgren血琼脂上进行，方法是将新鲜分离的菌落悬浮于脑心浸液肉汤中。除甲硝唑和氯霉素外，还试用了米诺环素、塞克硝唑、替硝唑、克拉霉素、罗红霉素等新型抗生素。甲硝唑、塞克硝唑、替硝唑和米诺环素等抗菌药物的敏感性为100%，其次是氯霉素、克拉霉素和罗红霉素。这些新型药物可作为治疗非芽孢厌氧菌的良好替代药物。