Bleiner D, Hametner K, Günther D
Laboratorium für Anorganische Chemie, ETH Zürich, Switzerland.
Fresenius J Anal Chem. 2000 Sep;368(1):37-44. doi: 10.1007/s002160000502.
Simultaneous ion sampling and sequential detection offered by inductively coupled plasma 'time of flight' mass spectrometry (ICP-TOFMS) provides advantages for the analysis of short transient concentration-variable signals as produced in laser ablation. In order to investigate the capabilities of ICP-TOFMS in combination with an excimer laser ablation system, ablation studies on reference materials and geological samples were carried out. Various ICP-TOFMS parameters were optimized for laser-induced aerosols. Transverse rejection ion pulse was used to extend the dynamic range in concentration. A reduced volume ablation cell was designed and used in order to increase the sample density in the ICP. Results for 63 simultaneously measured isotopes (SRM 610 from NIST) lead to limits of detection in the 1-100 microg/g range for a 80 microm crater diameter (10 Hz, 1.2 mJ pulse energy). The reproducibility of signal ratios was determined to be better than 2% RSD for transient signals using 102 ms integration time. These optimized parameters were then used for the analysis of tin-rich fluid inclusions. Preliminary results of multielement analysis and isotopic ratio determinations on individual fluid inclusions (63 isotopes, 102 ms integration time) demonstrate the capabilities of ICP-TOFMS in combination with laser ablation.
电感耦合等离子体“飞行时间”质谱仪（ICP - TOFMS）提供的同步离子采样和顺序检测，对于分析激光烧蚀产生的短瞬态浓度可变信号具有优势。为了研究ICP - TOFMS与准分子激光烧蚀系统结合的能力，对参考物质和地质样品进行了烧蚀研究。针对激光诱导气溶胶对各种ICP - TOFMS参数进行了优化。采用横向排斥离子脉冲来扩展浓度动态范围。设计并使用了一个体积减小的烧蚀池，以提高ICP中的样品密度。对63种同时测量的同位素（美国国家标准与技术研究院的SRM 610）的测量结果表明，对于直径80微米的弹坑（10赫兹，1.2毫焦脉冲能量），检测限在1 - 100微克/克范围内。对于瞬态信号，使用102毫秒积分时间时，信号比的重现性确定为优于2%相对标准偏差。然后将这些优化参数用于分析富锡流体包裹体。对单个流体包裹体进行多元素分析和同位素比测定的初步结果（63种同位素，102毫秒积分时间）证明了ICP - TOFMS与激光烧蚀结合的能力。
