Wong R K, Gregory R, Lo T C
Department of Integrated Medicine, Leicester Royal Infirmary, Leicester LE1 5WW, UK.
Int J Clin Pract. 2000 Nov;54(9):623-4.
A 76-year-old man presented with a subacute history of weight loss, malaise and anorexia. Laboratory investigations revealed serially increasing hypercalcaemia, correlating with deterioration in his clinical status. He was subsequently shown to have hypocortisolaemia, which improved with the administration of intravenous steroids. Subsequent biochemical testing revealed the endocrinological defect to be one of isolated ACTH deficiency, which, unlike Addison's disease, does not classically include hypercalcaemia in its presentation.
一名76岁男性,有体重减轻、不适和厌食的亚急性病史。实验室检查显示血钙水平持续升高,与他的临床状况恶化相关。随后发现他存在皮质醇水平低下,静脉注射类固醇后情况有所改善。后续生化检测显示内分泌缺陷为孤立性促肾上腺皮质激素(ACTH)缺乏,与艾迪生病不同,其典型表现中通常不包括高钙血症。