Maruzzi D, Marin A, Lenardon O, Ostardo E, Sangiorgio A, Merlo A, Garbeglio A
UO di Urologia, Dipartimento di Chirurgia 1a Azienda Ospedaliera S.ta Maria degli Angeli, Pordenone.
Arch Ital Urol Androl. 2000 Dec;72(4):174-81.
The diagnosis of prostate neoplasm is still limited today by the variable power of prediction of the three main surveys used: prostate-specific antigen (PSA), digito rectal exploration (DRE) and ultrasound transrectal (TRUS). The study aimed to estimate the benefits and the diagnostic impact of the color Doppler ultrasonography on the diagnosis of prostate neoplasm through biopsies targeted on areas with abnormal flow. With this purpose, 222 biopsies performed on 71 patients between 1997 and 1999 were considered, which led to a diagnosis of neoplasm in 36 patients. Of the 84 biopsies that revealed prostate adenocarcinoma, 74 (64.3%) were correlated to hypoechoic lesions with abnormal flow signals while 41 (35.6%) showed a benign pathology (prostatitis or benign prostatic hyperplasia) (p < 0.0011). In five patients (13%) who did not present any evident lesions at a first transrectal ultrasound, the diagnosis of neoplasm was made only through biopsies targeted on areas with abnormal flow. Therefore, the color Doppler exam can be used during prostate ultrasonography either to consolidate the diagnosis or to give a useful target in case of isoechoic lesions.
目前，前列腺肿瘤的诊断仍受到三种主要检查方法预测能力的限制，这三种检查方法分别是：前列腺特异性抗原（PSA）、直肠指诊（DRE）和经直肠超声检查（TRUS）。本研究旨在通过对血流异常区域进行活检，评估彩色多普勒超声对前列腺肿瘤诊断的益处和诊断影响。为此，研究人员回顾了1997年至1999年间对71例患者进行的222次活检，其中36例被诊断为肿瘤。在84例显示前列腺腺癌的活检中，74例（64.3%）与血流信号异常的低回声病变相关，而41例（35.6%）显示为良性病变（前列腺炎或良性前列腺增生）（p<0.0011）。在5例（13%）首次经直肠超声检查未发现明显病变的患者中，仅通过对血流异常区域进行活检才确诊为肿瘤。因此，彩色多普勒检查可在前列腺超声检查期间用于巩固诊断，或在等回声病变的情况下提供有用的活检靶点。
