Roy S A, Dear S P, Alloway K D
Department of Neuroscience and Anatomy, Penn State University College of Medicine, Hershey, Pennsylvania 17033-2255, USA.
J Neurosci. 2001 Mar 1;21(5):1795-808. doi: 10.1523/JNEUROSCI.21-05-01795.2001.
To determine whether neuronal oscillations are essential for long-range cortical synchronization in the somatosensory system, we characterized the incidence and response properties of gamma range oscillations (20-80 Hz) among pairs of synchronized neurons in primary (SI) and secondary (SII) somatosensory cortex. Synchronized SI and SII discharges, which occurred within a 3 msec period, were detected in 13% (80 of 621) of single-unit pairs and 25% (29 of 118) of multiunit pairs. Power spectra derived from the auto-correlation histograms (ACGs) revealed that approximately 15% of the neurons forming synchronized pairs were characterized by oscillations. Although 24% of the synchronized neuron pairs (19/80) were characterized by oscillations in one or both neurons, only 1% (1/80) of these pairs displayed oscillations at the same frequency in both neurons. Similar results were observed among pairs of multiunit responses. When single-trial responses were analyzed, the vast majority of responses still did not exhibit oscillations in the gamma frequency range. These results suggest that separate populations of cortical neurons can be bound together without being constrained by the phase relationships defined by specific oscillatory frequencies.
为了确定神经元振荡对于体感系统中远距离皮层同步是否至关重要，我们对初级体感皮层（SI）和次级体感皮层（SII）中同步神经元对之间伽马波段振荡（20 - 80赫兹）的发生率和反应特性进行了表征。在3毫秒内发生的同步SI和SII放电，在13%（621对单神经元对中的80对）的单神经元对和25%（118对多神经元对中的29对）的多神经元对中被检测到。从自相关直方图（ACG）得出的功率谱显示，形成同步对的神经元中约15%具有振荡特征。尽管24%的同步神经元对（19/80）在一个或两个神经元中具有振荡特征，但这些对中只有1%（1/80）在两个神经元中以相同频率振荡。在多神经元反应对中也观察到了类似结果。当分析单次试验反应时，绝大多数反应在伽马频率范围内仍未表现出振荡。这些结果表明，不同群体的皮层神经元可以在不受特定振荡频率定义的相位关系约束的情况下结合在一起。
