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特发性巨细胞性心肌炎——一种独特的临床病理实体。

Idiopathic giant cell myocarditis--a distinctive clinico-pathological entity.

作者信息

Davies M J, Pomerance A, Teare R D

出版信息

Br Heart J. 1975 Feb;37(2):192-5. doi: 10.1136/hrt.37.2.192.

DOI:10.1136/hrt.37.2.192
PMID:1122272
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC484100/
Abstract

Eleven cases of idiopathic giant cell myocarditis are described, The pathological features are unmistakable with serpiginous areas of myocardial necrosis, at the margins of which giant cells can be seen on histological examination. The aetiology of the condition remains obscure but associated pathology suggests that altered immunity may be a factor. The rapid clinical course is, however, highly suggestive of an infective cause though none has been found.

摘要

本文描述了11例特发性巨细胞性心肌炎。其病理特征明确,表现为心肌坏死的匐行性区域,组织学检查可见坏死边缘有巨细胞。该病的病因仍不清楚,但相关病理提示免疫改变可能是一个因素。然而,尽管尚未发现感染源,但其快速的临床病程强烈提示存在感染性病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e848/484100/8dbcb94dc682/brheartj00252-0090-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e848/484100/027a0ed2f4e3/brheartj00252-0089-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e848/484100/8dbcb94dc682/brheartj00252-0090-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e848/484100/027a0ed2f4e3/brheartj00252-0089-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e848/484100/8dbcb94dc682/brheartj00252-0090-a.jpg

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Br Heart J. 1965 May;27(3):458-61. doi: 10.1136/hrt.27.3.458.
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UNUSUAL GIANT CELL LESIONS IN BIOPSY SPECIMEN OF LEFT ATRIAL APPENDAGES IN MITRAL STENOSIS.二尖瓣狭窄患者左心耳活检标本中不寻常的巨细胞病变
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Immunomodulatory Therapy for Giant Cell Myocarditis: A Narrative Review.巨细胞性心肌炎的免疫调节治疗:一项叙述性综述。
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BMC Cardiovasc Disord. 2022 Apr 26;22(1):192. doi: 10.1186/s12872-022-02639-0.
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Surg Case Rep. 2021 Oct 20;7(1):226. doi: 10.1186/s40792-021-01309-1.
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