卵巢早衰的治疗理念

Treatment concepts for premature ovarian failure.

作者信息

van Kasteren Y

机构信息

Department of Obstetrics and Gynecology, Medical Center Alkmaar, Alkmaar, The Netherlands.

出版信息

J Soc Gynecol Investig. 2001 Jan-Feb;8(1 Suppl Proceedings):S58-9.

PMID:11223376

Abstract

Treatment concepts for premature ovarian failure concern restoration, preservation, and substitution of ovarian function. To date, there is no effective treatment to restore ovarian function. Preservation of ovarian function using cryopreservation and auto- or xenotransplantation will be possible in the near future. Regulation of the dynamics of the oocyte pool through GDF9 or AMH is not envisaged in the near future. Developments in estrogen receptor research may change treatment concepts in hormone replacement therapy.

摘要

卵巢早衰的治疗理念涉及卵巢功能的恢复、保存和替代。迄今为止，尚无恢复卵巢功能的有效治疗方法。在不久的将来，利用冷冻保存及自体或异种移植来保存卵巢功能将成为可能。近期内尚无通过生长分化因子9（GDF9）或抗缪勒管激素（AMH）来调控卵母细胞池动态变化的设想。雌激素受体研究的进展可能会改变激素替代疗法的治疗理念。