Ivy D, Eells P
Section of Cardiology, Pediatric Heart Lung Center, The Children's Hospital, University of Colorado Health Sciences Center, 1056 East 19th Avenue, Denver, CO 80218, USA.
Adolesc Med. 2001 Feb;12(1):79-93.
This article discusses diagnostic and therapeutic options of adolescents with primary and secondary pulmonary hypertension. Pulmonary hypertension is an important determinant of morbidity and mortality in many diseases, including congenital heart disease and respiratory disease. Previously, the diagnosis of pulmonary hypertension in children carried a poor prognosis. However, advances in the diagnosis and treatment of pulmonary hypertension over the last decade have markedly improved survival of many patients. A targeted approach includes treatment of the underlying disease, and therefore requires an extensive evaluation. Many of the treatment modalities are based on advanced understanding of basic pulmonary vascular biology.
本文讨论了原发性和继发性肺动脉高压青少年患者的诊断和治疗选择。肺动脉高压是包括先天性心脏病和呼吸系统疾病在内的许多疾病发病和死亡的重要决定因素。以前，儿童肺动脉高压的诊断预后较差。然而，过去十年中肺动脉高压诊断和治疗方面的进展显著提高了许多患者的生存率。一种有针对性的方法包括治疗潜在疾病，因此需要进行广泛评估。许多治疗方式都基于对肺血管基础生物学的深入理解。
