Cornacchia D, Fabbri M, Puglisi A, Moracchini P, Bernasconi M, Nastasi M, Menozzi C, Mascioli G, Marotta T, de Seta F
Cardiology Dept, Degli Infermi Hospital, Feanza RA, Italy.
Europace. 2000 Jul;2(3):240-4. doi: 10.1053/eupc.2000.0103.
One hundred and seventy-three patients, mean age 74 years permanently paced with 123 atrial (53 unipolar, 70 bipolar) and 143 ventricular (73 unipolar, 70 bipolar) pacing leads were included in this study. The pacing leads were recent generation low surface area steroid eluting leads from one manufacturer: leads with silicone and polyurethane insulation were studied, and they were combined with generations of one pacemaker family from the same manufacturer permitting identical measurements to be made over a follow-up of 2 years. Pacing threshold was measured using pulse duration at a fixed voltage of 1.5 V: peak to peak P and R wave amplitude and pacing impedance at 2.5 V and 0.5 ms were all measured using the manufacturer's standard programmer. Although many significant differences, in the parameters measures, existed between atrium and ventricle and unipolar and bipolar configurations, none was felt to be of clinical significance. These data permit the physician to choose the lead type with regard to sensing performance and long-term lead integrity.
本研究纳入了173例患者，平均年龄74岁，他们均采用永久性心脏起搏治疗，共植入123根心房起搏导线（53根单极，70根双极）和143根心室起搏导线（73根单极，70根双极）。起搏导线均为某一制造商生产的新一代低表面积类固醇洗脱导线：研究了带有硅胶和聚氨酯绝缘层的导线，并将其与同一制造商生产的同一型号起搏器相匹配，以便在2年的随访期内进行相同的测量。起搏阈值是在1.5V固定电压下使用脉宽进行测量的：峰峰值P波和R波振幅以及在2.5V和0.5ms时的起搏阻抗均使用制造商的标准程控仪进行测量。尽管在参数测量方面，心房与心室以及单极与双极配置之间存在许多显著差异，但均被认为无临床意义。这些数据使医生能够根据感知性能和导线长期完整性来选择导线类型。
