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大剂量腺苷和维拉帕米局部灌注成功治疗顽固性无复流——病例报告

Refractory no-reflow successfully treated with local infusion of high-dose adenosine and verapamil--a case report.

作者信息

Dillon W C, Hadian D, Ritchie M E

机构信息

Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis 46202, USA.

出版信息

Angiology. 2001 Feb;52(2):137-41. doi: 10.1177/000331970105200208.

DOI:10.1177/000331970105200208
PMID:11228087
Abstract

No-reflow is an unpredictable complication following percutaneous coronary intervention. No-reflow is associated with myocardial ischemia and infarction and increased mortality. A case of refractory no-reflow is described that was rapidly and successfully treated with multiple infusions of high doses of verapamil and adenosine applied directly at the site of no-reflow through a perfusion catheter.

摘要

无复流是经皮冠状动脉介入治疗后一种不可预测的并发症。无复流与心肌缺血、梗死及死亡率增加相关。本文描述了一例难治性无复流病例,通过灌注导管在无复流部位直接多次输注高剂量维拉帕米和腺苷,迅速且成功地进行了治疗。

相似文献

1
Refractory no-reflow successfully treated with local infusion of high-dose adenosine and verapamil--a case report.大剂量腺苷和维拉帕米局部灌注成功治疗顽固性无复流——病例报告
Angiology. 2001 Feb;52(2):137-41. doi: 10.1177/000331970105200208.
2
[The no-reflow phenomenon and its clinical significance].
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3
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Catheter Cardiovasc Interv. 2010 Nov 15;76(6):787-93. doi: 10.1002/ccd.22724. Epub 2010 Aug 24.
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Intracoronary verapamil for reversal of no-reflow during coronary angioplasty for acute myocardial infarction.冠状动脉内注射维拉帕米用于急性心肌梗死冠状动脉成形术中无复流现象的逆转。
Catheter Cardiovasc Interv. 2002 Dec;57(4):444-51. doi: 10.1002/ccd.10375.
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Treating acute "no-reflow" with intracoronary adenosine in 4 patients during percutaneous coronary intervention.在4例患者经皮冠状动脉介入治疗期间,使用冠状动脉内腺苷治疗急性“无复流”。
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Effects of verapamil and adenosine in an adjunct to tirofiban on resolution and prognosis of noreflow phenomenon in patients with acute myocardial infarction.维拉帕米和腺苷联合替罗非班对急性心肌梗死患者无复流现象的缓解及预后的影响。
Minerva Cardioangiol. 2014 Oct;62(5):389-97. Epub 2014 Apr 3.
8
Pretreatment with intragraft verapamil prior to percutaneous coronary intervention of saphenous vein graft lesions: results of the randomized, controlled vasodilator prevention on no-reflow (VAPOR) trial.在隐静脉桥病变经皮冠状动脉介入治疗前,采用移植物内维拉帕米预处理:血管扩张剂预防无复流(VAPOR)随机对照试验的结果
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No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention.无复流是经皮冠状动脉介入治疗后死亡和心肌梗死的独立预测因素。
Am Heart J. 2003 Jan;145(1):42-6. doi: 10.1067/mhj.2003.36.
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Comparison of combination therapy of adenosine and nitroprusside with adenosine[correction for adensosine] alone in the treatment of angiographic no-reflow phenomenon: does 1 plus 1 equal 11?腺苷与硝普钠联合治疗与单独使用腺苷[应为腺苷]治疗血管造影无复流现象的比较:1加1等于11吗?
Catheter Cardiovasc Interv. 2004 Apr;61(4):492-3. doi: 10.1002/ccd.20023.

引用本文的文献

1
Adenosine and verapamil for no-reflow during primary percutaneous coronary intervention in people with acute myocardial infarction.急性心肌梗死患者在直接经皮冠状动脉介入治疗期间使用腺苷和维拉帕米治疗无复流现象。
Cochrane Database Syst Rev. 2015 May 18;2015(5):CD009503. doi: 10.1002/14651858.CD009503.pub3.
2
Distal administration of very high doses of intracoronary adenosine for the treatment of resistant no-reflow.冠状动脉内给予极高剂量腺苷进行远端给药以治疗顽固性无复流。
Exp Clin Cardiol. 2008 Fall;13(3):141-3.
3
Coronary No-reflow Phenomenon.
冠状动脉无复流现象
Curr Treat Options Cardiovasc Med. 2005 May;7(1):75-80. doi: 10.1007/s11936-005-0008-0.