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来自同一对肺不同部位的样本中肺孢子虫甾醇谱的异质性表明存在不同生物体群体的混合感染。

Heterogeneity of Pneumocystis sterol profiles of samples from different sites in the same pair of lungs suggests coinfection by distinct organism populations.

作者信息

Amit Z, Kaneshiro E S

机构信息

Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221, USA.

出版信息

J Clin Microbiol. 2001 Mar;39(3):1137-9. doi: 10.1128/JCM.39.3.1137-1139.2001.

Abstract

Sterol profiles of samples taken from different sites of a Pneumocystis-infected human lung showed large variations in pneumocysterol similar to those that occur among samples from different patients. Thus, the influence of diet or drugs on pneumocysterol accumulation was ruled out, suggesting distinct phenotypic populations as the basis for the heterogeneity.

摘要

从感染肺孢子菌的人类肺部不同部位采集的样本的甾醇谱显示,肺孢子菌甾醇存在很大差异,类似于不同患者样本之间的差异。因此,饮食或药物对肺孢子菌甾醇积累的影响被排除,这表明不同的表型群体是这种异质性的基础。

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本文引用的文献

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Lipid metabolism of Pneumocystis: toward the definition of new molecular targets.
FEMS Immunol Med Microbiol. 1998 Sep;22(1-2):135-43. doi: 10.1111/j.1574-695X.1998.tb01198.x.
8
Typing methods to approach Pneumocystis carinii genetic heterogeneity.探讨卡氏肺孢子虫基因异质性的分型方法。
FEMS Immunol Med Microbiol. 1998 Sep;22(1-2):27-35. doi: 10.1111/j.1574-695X.1998.tb01184.x.
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