Thomsen T, Hugdahl K, Ersland L, Barndon R, Lundervold A, Smievoll A I, Roscher B E, Sundberg H
Department of Biological and Medical Psychology, University of Bergen, Aarstadveien 21 N-5009 Bergen, Norway.
Med Sci Monit. 2000 Nov-Dec;6(6):1186-96.
The main purpose of the present study was to: 1) to investigate differences between males and females in brain activation when performing a mental rotation task, 2) investigate hemisphere differences in brain activation during mental rotation. Brain activation was measured with functional magnetic resonance imaging (fMRI). Image acquisition was performed with a 1.5 Tesla Siemens Vision MR scanner equipped with 25 m T/m gradients. Scanning of anatomy was done with a T1-weighted 3D FLASH pulse sequence. Serial imaging with 70 BOLD sensitive echo planar (EPI) whole brain measurements was done during stimulus presentations, divided into 7 blocks of 10 EPI multi-slice volume measurements each. Eleven subjects were presented with black-and-white drawings of 3-D shapes taken from the set of 3-D perspective drawings developed by Shepard and Metzler [1], alternated with 2-D white bars as control stimuli. In the experimental condition, the subjects were shown 36 pairs of 3-D drawings, presented in three blocks of 12 pairs of drawings. The drawings were always presented pairwise. On half of the trials, the two 3-D shapes were congruent but portrayed with different orientation, in the other half the two shapes were incongruent. MR data were analyzed with the SPM-96 analysis software. After subtraction of activity related to the 2-D control stimuli, clusters of significant activation were found in the superior parietal lobule (BA 7), more intensely over the right hemisphere, and bilaterally in the inferior frontal gyrus (BA 44/45). Males showed predominantly parietal activation, while the females showed inferior frontal activation. It is suggested that males and females may differ in the processing strategy used when approaching a 3-D mental rotation task, males using a 'gestalt' strategy and females using a 'serial' reasoning strategy.
1）调查男性和女性在执行心理旋转任务时大脑激活的差异，2）研究心理旋转过程中大脑激活的半球差异。通过功能磁共振成像（fMRI）测量大脑激活。图像采集使用配备25 m T/m梯度的1.5特斯拉西门子Vision MR扫描仪进行。解剖结构扫描采用T1加权3D FLASH脉冲序列。在刺激呈现期间进行70次BOLD敏感回波平面（EPI）全脑测量的序列成像，分为7个块，每个块有10次EPI多层体积测量。向11名受试者展示从Shepard和Metzler [1]开发的3D透视图集中选取的3D形状的黑白绘图，并与2D白条交替作为对照刺激。在实验条件下，向受试者展示36对3D绘图，分为三个块，每个块有12对绘图。绘图总是成对呈现。在一半的试验中，两个3D形状是一致的，但方向不同，在另一半试验中，两个形状不一致。使用SPM - 96分析软件对MR数据进行分析。减去与2D对照刺激相关的活动后，在顶上小叶（BA 7）发现显著激活簇，在右半球更强烈，并且在双侧额下回（BA 44/45）也有激活。男性主要表现为顶叶激活，而女性表现为额下回激活。这表明男性和女性在处理3D心理旋转任务时使用的策略可能不同，男性使用“格式塔”策略，女性使用“串行”推理策略。
