Rodriguez-Ferrera S, McCarthy R A, McKenna P J
Fulbourn Hospital, Addenbrooke's NHS Trust Cambridge and Department of Experimental Psychology, University of Cambridge.
Psychol Med. 2001 Feb;31(2):197-205. doi: 10.1017/s003329170100321x.
Although poor language test performance has been documented in schizophrenia, its relationship to formal thought disorder remains unclear.
Forty schizophrenic patients were administered eight language tests and, under blind conditions, rated for formal thought disorder. Measures of general intellectual function were also obtained.
Performance on all language tests was significantly correlated with the general intellectual measures. Three language test scores also showed significant correlations with formal thought disorder scores. Multiple regression and analysis of intellectually preserved patients suggested particular associations of formal thought disorder with semantic comprehension and picture description.
General intellectual impairment is an important determinant of poor language test performance in schizophrenia, but presence of formal thought disorder may also contribute. A higher-order semantic deficit may be particularly relevant to both linguistic impairment and formal thought disorder.
尽管精神分裂症患者语言测试表现不佳已有记录,但它与形式思维障碍的关系仍不明确。
对40名精神分裂症患者进行了八项语言测试,并在盲态条件下对形式思维障碍进行评分。还获得了一般智力功能的测量结果。
所有语言测试的表现均与一般智力测量结果显著相关。三项语言测试分数也与形式思维障碍分数显著相关。对智力保留患者的多元回归分析表明,形式思维障碍与语义理解和图片描述存在特定关联。
一般智力损害是精神分裂症患者语言测试表现不佳的重要决定因素,但形式思维障碍的存在也可能起作用。高阶语义缺陷可能与语言障碍和形式思维障碍都特别相关。