Mortimore R J, Whitehead K J
Sullivan and Nicolaides Pathology, PO Box 344, Indooroopilly, Old 4068, Australia.
Australas J Dermatol. 2001 Feb;42(1):22-5. doi: 10.1046/j.1440-0960.2001.00467.x.
Dermatomyofibroma is a recently described plaque-like dermal tumour composed of myofibroblasts that usually presents around the shoulder, axilla and posterior neck, often in young adult females. Here, we present two cases, one from the posterior axilla of a 33-year-old female and one from the posterior neck of a 7-year-old male. Both were clinically red-brown lesions with histological and immunohistochemical features diagnostic of dermatomyofibroma. There was no evidence of aggressive biologic behaviour with 3 months and 2 months follow up, respectively. While the majority of dermatomyofibromas present in postpubescent females, the 7-year-old male exemplifies a subgroup occurring in male children which appears to show a particular predilection for the posterior neck.
皮肤肌纤维瘤是一种最近才被描述的斑块状真皮肿瘤,由肌成纤维细胞组成,通常出现在肩部、腋窝和后颈部,多见于年轻成年女性。在此,我们报告两例病例,一例来自一名33岁女性的腋窝后部,另一例来自一名7岁男性的后颈部。两例临床均表现为红棕色皮损,组织学和免疫组化特征均诊断为皮肤肌纤维瘤。分别随访3个月和2个月,均未发现侵袭性生物学行为的证据。虽然大多数皮肤肌纤维瘤发生于青春期后的女性,但这名7岁男性的病例代表了发生于男童的一个亚组,该亚组似乎特别好发于后颈部。