Maruyama K, Koizumi T
Division of Neonatology, Gunma Children's Medical Center, Gunma, Japan.
J Perinat Med. 2001;29(1):64-70. doi: 10.1515/JPM.2001.009.
In order to elucidate intestinal blood flow after birth in infants with intrauterine growth retardation, we measured superior mesenteric artery blood flow velocity in uncomplicated small for gestational age infants with a birth weight of < 1500 g by pulsed Doppler ultrasound in days 1 to 7 of life. Peak systolic blood flow velocity, time-averaged mean blood flow velocity and end-diastolic blood flow velocity in the superior mesenteric artery significantly increased with time. The resistance index and relative vascular resistance in the superior mesenteric artery significantly decreased after birth. Compared with gestational age matched appropriate for gestational age infants and birth weight matched appropriate for gestational age ones, peak systolic blood flow velocity, time-averaged mean blood flow velocity and end-diastolic blood flow velocity in the superior mesenteric artery were lower in the small for gestational age infants. The difference between the small for gestational age group and the gestational age matched appropriate for gestational age group was statistically significant. The resistance index and relative vascular resistance in the superior mesenteric artery tend to be higher in the small for gestational age group than in the appropriate for gestational age groups. In conclusion, although intestinal blood flow velocity in infants with intrauterine growth retardation increases after birth, it is lower than appropriate for gestational age infants during the early neonatal period.
为了阐明宫内生长受限婴儿出生后的肠道血流情况，我们在出生体重<1500g的单纯小于胎龄儿出生后第1至7天，通过脉冲多普勒超声测量了肠系膜上动脉血流速度。肠系膜上动脉的收缩期峰值血流速度、时间平均平均血流速度和舒张末期血流速度随时间显著增加。出生后肠系膜上动脉的阻力指数和相对血管阻力显著降低。与胎龄匹配的适于胎龄儿和出生体重匹配的适于胎龄儿相比，小于胎龄儿肠系膜上动脉的收缩期峰值血流速度、时间平均平均血流速度和舒张末期血流速度较低。小于胎龄组与胎龄匹配的适于胎龄组之间的差异具有统计学意义。小于胎龄组肠系膜上动脉的阻力指数和相对血管阻力往往高于适于胎龄组。总之，尽管宫内生长受限婴儿的肠道血流速度在出生后增加，但在新生儿早期低于适于胎龄儿。
