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关于肥胖的成因及后果的十个问题:应激激素

[Ten questions on the causes and consequences of obesity: stress hormones].

作者信息

Martin-Du Pan R C, Héraïef E

出版信息

Rev Med Suisse Romande. 2001 Jan;121(1):51-5.

PMID:11234710
Abstract

In Switzerland, 6% of men and 5% of women are obese (BMI > 30); 33% of men and 17% of women are overweight (BMI 25-30). Both genetic and environmental factors are responsible for obesity. There is an increased risk of C-V disease, diabetes and steato-hepatitis in abdominal obesity (abdominal circumference > 102 cm for men and > 88 cm for women). There is also an increased level of cortisol, which could be due to a difficulty to cope with psycho-social stress. Leptine and different hormones play a role in fat storage. Menopause and pregnancy are moderate risk factors for obesity. Weight gain may also result from different drugs, smoking cessation and stress. Eating disorders such as boulimia and binge eating must be diagnosed and treated. Beneficial health effect of weight loss is analysed.

摘要

在瑞士,6%的男性和5%的女性肥胖(体重指数>30);33%的男性和17%的女性超重(体重指数25 - 30)。遗传和环境因素均导致肥胖。腹部肥胖(男性腹围>102厘米,女性腹围>88厘米)会增加患心血管疾病、糖尿病和脂肪性肝炎的风险。皮质醇水平也会升高,这可能是由于难以应对心理社会压力所致。瘦素和其他不同激素在脂肪储存中起作用。更年期和怀孕是导致肥胖的中度风险因素。体重增加也可能由不同药物、戒烟和压力引起。必须诊断和治疗诸如神经性贪食症和暴饮暴食等饮食失调症。分析了减肥对健康的有益影响。

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